Under high tryptophan conditions, tryptophan binds to and activates the repressor protein, thereby blocking transcription of the trp operon. This is an example of:

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Quizplus · Accepted Answer

This is an example of negative control of repressible genes because the presence of tryptophan (the product of the trp operon) activates the repressor protein, which in turn binds to the operator region of the trp operon, preventing transcription. This is a classic feedback inhibition mechanism where the end product of a pathway inhibits its own synthesis by repressing gene expression.

Under High Tryptophan Conditions, Tryptophan Binds to and Activates the Repressor