You are genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have sickle-cell anemia. Genetic tests reveal that both the man and woman are carriers for sickle-cell anemia. How should you advise them?
A) Half of their children will have sickle-cell anemia, and the other half will be carriers.
B) All of their children will have sickle-cell anemia.
C) There are no concerns, because none of their offspring have a chance of inheriting the sickle-cell allele.
D) While none of their children will have sickle-cell anemia, each child will have a 50% chance of being a carrier.
E) All of their children will have a 25% chance of having sickle-cell anemia.
Correct Answer:
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