The nurse educator is completing a staff education conference about prenatal carrier screening. Which statement by a participant indicates a correct understanding of the genetic inheritance for cystic fibrosis?

Question

The nurse educator is completing a staff education conference about prenatal carrier screening.  Which statement by a participant indicates a correct understanding of the genetic inheritance for cystic fibrosis?

Quizplus · Accepted Answer

11ecbb05_ca54_5e1a_b433_bb1809ececc5_MD0009_00 Carrier screening offers clients who are unaffected by a genetic disorder the option to discover whether they possess an abnormal gene (ie, are carriers) that may affect health outcomes of future offspring. This type of genetic testing is frequently offered preconceptionally/prenatally to guide pregnancy decision-making. Cystic fibrosis follows an autosomal recessive inheritance pattern, meaning that offspring must receive two abnormal genes (one from each parent) to be affected with the disorder (Option A). Other disorders following this inheritance pattern include phenylketonuria, Tay-Sachs disease, and sickle cell disease. (Option B) Male and female offspring have the same likelihood of inheriting autosomal recessive disorders because the abnormal gene is not linked to a sex chromosome. (Option C) X-linked recessive disorders (eg, hemophilia, Duchenne muscular dystrophy) most often affect male offspring. This inheritance pattern occurs because male offspring who receive an abnormal sex chromosome from a female carrier (ie, X chromosome) will have the disorder because, unlike female offspring, they only have one X chromosome. (Option D) Because carriers with no evidence of the disorder can pass an abnormal gene to offspring, autosomal recessive conditions may not present in every generation. However, autosomal dominant inheritance patterns (eg, Huntington disease, achondroplasia) are noted in each previous generation because affected offspring must have an affected parent. Educational objective: Cystic fibrosis is a disorder with an autosomal recessive inheritance pattern. Affected offspring must inherit two abnormal genes (one from each parent). Male and female offspring are equally affected because the disorder is not sex-linked.

The Nurse Educator Is Completing a Staff Education Conference About