An 8-year-old male is brought to his pediatrician's office by his mother. The child has had a runny nose, sore throat, cough, and low-grade fever for the past 24 hours. The patient's mother recalls that several of the child's friends have been ill recently with similar symptoms. The mother asks whether the child will need antibiotics for his condition. His pediatrician recommends symptomatic therapy and feels that his illness is most likely of viral etiology. Cytotoxic CD8+ lymphocytes are able to kill virus-infected nasal epithelial cells once sensitized. Cytotoxic CD8+ lymphocyte receptors recognize foreign proteins on the epithelial cell surface. Foreign proteins are presented on the epithelial cell surface by MHC molecules. These MHC molecules comprise which of the following components?
A) MHC class I heavy chain only
B) MHC class I heavy chain and B2-microglobulin
C) MHC class I heavy chain and IgG
D) MHC class II alpha-chain and beta-chain
E) MHC class II alpha-chain only
Correct Answer:
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