A 28-year-old primigravid woman comes to the office for a routine prenatal checkup at 28 weeks gestation. The patient has no concerns and has had an uneventful pregnancy to date. Physical examination shows a uterine size concordant with ultrasound dates, and fetal cardiac activity is in the normal range. After reviewing the results of her laboratory evaluations, the physician administers an injection of anti-Rh(D) immunoglobulin. The administered antibodies most likely belong to which of the following immunoglobulin classes?

Question

A 28-year-old primigravid woman comes to the office for a routine prenatal checkup at 28 weeks gestation.  The patient has no concerns and has had an uneventful pregnancy to date.  Physical examination shows a uterine size concordant with ultrasound dates, and fetal cardiac activity is in the normal range.  After reviewing the results of her laboratory evaluations, the physician administers an injection of anti-Rh(D) immunoglobulin.  The administered antibodies most likely belong to which of the following immunoglobulin classes?

Quizplus · Accepted Answer

Eductional Objective: Anti-Rh immunoglobulin consists of anti-D IgG antibodies that bind to Rh-positive fetal erythrocytes, promoting clearance by maternal reticuloendothelial macrophages and preventing maternal Rh sensitization.  It is routinely administered to Rh-negative women during gestation and immediately postpartum.

A 28-Year-Old Primigravid Woman Comes to the Office for a Routine