A 28-year-old woman comes to the hospital because of a 4-day history of lower abdominal and confusion . Her temperature is 39.7°C , blood pressure is 80/44 mm Hg and respirations are 28/min. There is tenderness to palpation over the pelvic region. On mental status examination, she is oriented only to person. Her urine dipstick is positive for leukocyte esterase and nitrites. Few hours later, the patient becomes progressively shorten of breath and requires mechanical ventilation. This patient's respiratory symptoms are most likely due to which of the following pathologic conditions?

Question

A 28-year-old woman comes to the hospital because of a 4-day history of lower abdominal and confusion . Her temperature is 39.7°C , blood pressure is 80/44 mm Hg and respirations are 28/min. There is tenderness to palpation over the pelvic region. On mental status examination, she is oriented only to person. Her urine dipstick is positive for leukocyte esterase and nitrites. Few hours later, the patient becomes progressively shorten of breath and requires mechanical ventilation.  This patient's respiratory symptoms are most likely due to which of the following pathologic conditions?

Quizplus · Accepted Answer

Eductional Objective: Acute respiratory distress syndrome is caused by injury of the pulmonary epithelium and/or endothelium, and occurs most often due to sepsis or pneumonia.  Cytokines recruit neutrophils to the lung tissue, which cause capillary damage and leakage of protein-rich fluid into the alveoli.  Later, cellular proliferation and collagen deposition occurs, and in some patients, this leads to irreversible pulmonary fibrosis.

A 28-Year-Old Woman Comes to the Hospital Because of a 4-Day