A 59-year-old guy arrives at the clinic complaining of back discomfort and three months of increased weariness. Back discomfort is mostly brought on by movement or changes in posture. Upon physical examination, the middle and lower backs are painful along the midline. According to a laboratory analysis, the serum calcium level is 12 mg/dL and the hemoglobin level is 10.2 g/dL. The results of a bone marrow aspiration are displayed below, along with the histopathological findings. This patient is at greatest risk for developing which of the following conditions?

Question

A 59-year-old guy arrives at the clinic complaining of back discomfort and three months of increased weariness. Back discomfort is mostly brought on by movement or changes in posture. Upon physical examination, the middle and lower backs are painful along the midline. According to a laboratory analysis, the serum calcium level is 12 mg/dL and the hemoglobin level is 10.2 g/dL. The results of a bone marrow aspiration are displayed below, along with the histopathological findings.  This patient is at greatest risk for developing which of the following conditions?

Quizplus · Accepted Answer

Eductional Objective: Multiple myeloma and other monoclonal plasma cell dyscrasias are linked to amyloid light-chain amyloidosis because of the deposition of soluble immunoglobulin light-chain fibrils in important organs (eg, kidneys, heart, neurologic system). Having more than 10% plasma cells in a bone marrow sample is highly predictive of multiple myeloma.

A 59-Year-Old Guy Arrives at the Clinic Complaining of Back