A 50-year-old woman, gravida 0 para 0, arrives at the office for a check-up. She has no cancer in her family. Breast examination is commonplace. A screening mammogram detects microcalcifications in the patient. She had a breast biopsy as a result of this discovery. Histopathology exhibits pleomorphic cells distended ducts with significant central necrosis. The lesion is limited to the ductal basal membrane. Which of the following is the most likely cause of the lesion?

Question

Quizplus · Accepted Answer

Eductional Objective: Ductal carcinoma in situ is characterized by ducts distended by pleomorphic cells with prominent central necrosis  that do not penetrate the basement membrane.  It is the precursor to invasive ductal carcinoma, the most common type of breast cancer

A 50-Year-Old Woman, Gravida 0 Para 0, Arrives at the Office