A 40-Year-Old Woman Comes to the Emergency Department Because of Difficulty

A 40-year-old woman comes to the emergency department because of difficulty walking for the past 4 hours. She first noticed her symptoms after getting up this morning and she was dragging her right foot while walking. She feels tired. She has a history of chronic sinusitis. Six months ago, she was diagnosed with asthma. Current medications include an albuterol inhaler and inhaled corticosteroids. Her temperature is 38.9°C (102°F) , pulse is 80/min, and her blood pressure is 140/90 mm Hg. Auscultation of her lungs shows diffuse wheezing over bilateral lung fields. Physical examination shows tender subcutaneous nodules on the extensor surfaces of the elbows. There are palpable, nonblanching erythematous lesions on both shins. Dorsiflexion of the right foot is impaired. Sensation to pinprick, light touch, and vibration is decreased over the ulnar aspect of the left forearm. Laboratory studies show: Serum antibodies against neutrophil myeloperoxidase are positive.  This patient most likely has which of the following conditions?

A) Allergic bronchopulmonary aspergillosis
B) Anti-glomerular basement membrane antibody disease
C) Carpal tunnel syndrome
D) Eosinophilic granulomatosis with polyangiitis
E) Idiopathic pulmonary fibrosis
F) Systemic sclerosis