A 45-year-old woman comes to the physician because of a 1-year history of episodic abdominal cramps, bloating, and flatulence. The symptoms worsen when she has pizza or ice cream and have become more frequent over the past 4 months. There is no associated weight loss, abnormal bleeding, or joint pain. Past medical history is otherwise unremarkable, though the patient has not seen a physician for many years. Vital signs and physical examination are normal. Laboratory studies show normal hemoglobin, iron, and vitamin D levels. A biopsy sample of this patient's small bowel mucosa would most likely show which of the following?
A) Atrophy of the intestinal villi
B) Collections of neutrophils within crypt lumina
C) Distended macrophages in lamina propria
D) Infiltration of lamina propria with atypical lymphocytes
E) Inflammation with scattered noncaseating granulomas
F) Normal intestinal mucosa
Correct Answer:
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