A 65-year-old man comes to the hospital due to severe left eye pain and decreased vision of the left eye, along with nausea and vomiting.t. Past medical history is notable for hypertension and type 2 diabetes mellitus, for which he takes appropriate medications. Ophthalmologic examination shows a fixed, mid-dilated pupil and a narrowed anterior chamber of the left eye. After discussion of treatment options, the patient is initiated on timolol ophthalmic drops. Which of the following structures is the most likely target of this medication?

Question

A 65-year-old man comes to the hospital due to severe left eye pain and decreased vision of the left eye, along with nausea and vomiting.t.  Past medical history is notable for hypertension and type 2 diabetes mellitus, for which he takes appropriate medications. Ophthalmologic examination shows a fixed, mid-dilated pupil and a narrowed anterior chamber of the left eye. After discussion of treatment options, the patient is initiated on timolol ophthalmic drops.  Which of the following structures is the most likely target of this medication?

Quizplus · Accepted Answer

Eductional Objective: Open-angle glaucoma is characterized by progressive loss of peripheral vision from elevated intraocular pressure.  Timolol and other nonselective beta blockers work by diminishing the secretion of aqueous humor by the ciliary epithelium.  Acetazolamide, a carbonic anhydrase inhibitor, also decreases aqueous humor secretion by the ciliary epithelium.  Prostaglandin F2a(eg, latanoprost, travoprost) and cholinomimetics (eg, pilocarpine, carbachol) decrease intraocular pressure by increasing the outflow of aqueous humor.

A 65-Year-Old Man Comes to the Hospital Due to Severe