A 40-year-old man comes to the physician because of a 2-day history of progressively blurred vision. He also reports seeing flashing lights in his visual field. He does not have any pain.The patient was diagnosed with sexually acquired HIV infection 4 years ago. Examination shows right conjunctival injection. Visual acuity is 20/20 in the left eye and 20/100 in the right eye. Fundoscopic examination of the right eye is shown. His CD4+ T-lymphocyte count is 46/mm3. Which of the following is the most appropriate pharmacotherapy for this patient's eye condition?

Question

A 40-year-old man comes to the physician because of a 2-day history of progressively blurred vision. He also reports seeing flashing lights in his visual field. He does not have any pain.The patient was diagnosed with sexually acquired HIV infection 4 years ago. Examination shows right conjunctival injection. Visual acuity is 20/20 in the left eye and 20/100 in the right eye. Fundoscopic examination of the right eye is shown.  His CD4+ T-lymphocyte count is 46/mm3. Which of the following is the most appropriate pharmacotherapy for this patient's eye condition?

Quizplus · Accepted Answer

Eductional Objective: Cytomegalovirus retinitis can cause blurring, vision loss, floaters, and photopsia (flashing lights) in patients with untreated AIDS who have CD4 counts <50/mm3. . funduscopy reveals yellow-white, fluffy retinal lesions near the retinal vessels with associated hemorrhage. Other first-line systemic therapies include ganciclovir, foscarnet, and cidofovir. Patients with acutely sight-threatening disease (e.g., lesions < 1.5 mm from the fovea or adjacent to the optic nerve head) should also receive intravitreal therapy with ganciclovir or foscarnet.

A 40-Year-Old Man Comes to the Physician Because of a 2-Day