During a Hysterectomy of 56 Year Old Women, a Severe

During a hysterectomy of 56 year old women, a severe bleeding occurred and Blood pressure is 80/40 mm Hg and pulse is 110/min. Immediate resuscitation efforts are initiated, during which she receives transfusion of several units of packed red blood cells. The patient has no significant medical history and takes no medications. After surgery , the patient reports a tingling sensation in his fingers and toes. Serum ionized calcium level is 4.2 mg/dL (normal: 4.8-5.5) . Which of the following is the most likely cause of this patient's current symptoms?

A) Antibody-mediated red blood cell membrane damage
B) Calcium chelation by a substance in the transfused blood
C) Electrolyte leakage from red blood cells during pretransfusion storage
D) Increased renal tubular excretion of calcium
E) Release of intracellular contents from injured muscle