Lipinski "Rule of Five" aims to correlate a drug candidate's physico-chemical parameters with its absorption,permeability,and pharmacologic efficacy. According to Lipinski's "Rule of Five",Oil/water distribution coefficient (LogP) has to be:
A) ≤ 1
B) ≥ 1
C) ≤ 5
D) ≥ 5
Correct Answer:
Verified
Q4: The brain capillaries generally have _.
A) high
Q5: Factors limiting drug penetration into the brain
Q6: Occludin,claudins and intercellular junctional adhesion molecules are
Q7: While there are restrictions for compounds to
Q8: _ is a common measure of lipophilicity
Q10: According to Lipinski's "Rule of Five",the number
Q11: According to Lipinski's "Rule of Five",the number
Q12: For successful CNS therapy,the Active Pharmaceutical Ingredient
Q13: For successful CNS therapy,the Active Pharmaceutical Ingredient
Q14: For successful CNS therapy,the Active Pharmaceutical Ingredient
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents