Based on their risk profile for developing an ipsilateral or contralateral breast cancer, whom should practitioners refer for an ipsilateral mastectomy, a contralateral prophylactic mastectomy, and/or a prophylactic bilateral salpingo-oophorectomy?

Question

Quizplus · Accepted Answer

BRCA positive, premenopausal women with a previous cancer diagnosis are at the greatest risk for developing a new contralateral cancer or new primary in the ipsilateral breast. BRCA positive, pre-and-postmenopausal patients with no personal history of breast cancer are still at risk and may benefit from one or both of these surgical procedures, but they are not at as great of a risk. BRCA positive, postmenopausal patients with a previous cancer diagnosis will not see the same benefits as premenopausal women.

Based on Their Risk Profile for Developing an Ipsilateral or Contralateral