A 25-year-old African American male is in the hospital recovering from a cholestectomy performed a day ago and is now complaining of priapism. He states that he noticed it around lunch time today and says that it has not gone down for the past couple hours. He mentions that he had a similar incident while visiting the Rocky Mountains on a skiing trip and went to the ER there and was told he had some kind of disease of the blood where his hemoglobin gene was defective.
You order a full lab-workup along with a solubility test to screen for HbS. CBC showed a normocytic anemia and solubility test was positive. The solubility test does not differentiate between sickle cell disease, sickle cell trait, and hemoglobin SC disease. You order a hemoglobin electrophoresis. The results of the electrophoresis will not be known for a couple days.
What lab results will show a notable differentiation between hemoglobin SS and hemoglobin SC disease?
A) Hemoglobin levels
B) Platelet count
C) Hematocrit
D) Iron levels
Correct Answer:
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