A specific germline mutation in the p53 tumor suppressor gene is responsible for more than 90% of Brazilian cases of adrenal cortical carcinoma in children.

Name: A specific germline mutation in the p53 tumor suppressor gene is responsible for more than 90% of Brazilian cases of adrenal cortical carcinoma in children.
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Question

Quizplus · Accepted Answer

The R337H germline mutation in the p53 gene is prevalent in southern Brazil and is associated with a high incidence of adrenal cortical carcinoma in children in that region.

A Specific Germline Mutation in the P53 Tumor Suppressor Gene