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Phorbol Esters Have Been Observed to Reduce the Transcription of AP-1

Question 69

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Phorbol esters have been observed to reduce the transcription of AP-1 genes. Explain how this process could occur. What are the consequences of AP-1 transcription? What role does intermittent exposure to phorbol esters have on an individual's health?

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Phorbol esters mimic the action of DAG, ...

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