In the Blood Cell Cancer or Leukemia Described in the Text

In the blood cell cancer or leukemia described in the text, how does cell division go out of control?

A) The Herceptin gene which normally regulates cell division mutates and stops working.
B) The proto-oncogene ras, which normally stops cell division, mutates and so the gene NF-1 allows cell division to go on uncontrolled.
C) The accelerator gene ras which normally allows cell division to occur mutates and stops working.
D) The Philadelphia Chromosome gene is permanently stuck "on" and the cell divides out of control.
E) The tumor suppressor gene NF-1 mutates so it can't do its job of stopping the proto-oncogene ras, from forcing uncontrolled cell division.