One of the Mechanisms Through Which Long-Term Changes to the Rate

One of the mechanisms through which long-term changes to the rate of neurotransmitter synthesis are achieved is

A) the production of new receptors for neurotransmitter reuptake.
B) the synthesis of new enzymes involved in neurotransmitter production.
C) the production of g-protein coupled receptors used for inhibitory feedback.
D) a reduction in the electrical excitability of neurons.
E) an increase the efficiency with which neurotransmitters are packed into vesicles.