Which of the following is or appears to be controlled by Blimp-1 during plasma cell differentiation?

Question

Quizplus · Accepted Answer

Blimp-1 is a transcriptional repressor that plays a crucial role in the differentiation of B cells into plasma cells. During this process, Blimp-1 controls several aspects: it promotes the exit from the cell cycle, facilitating the transition of B cells into antibody-secreting plasma cells; it regulates the switch from membrane-bound IgM to secreted IgM, which is essential for the effective secretion of antibodies; and it is involved in the downregulation of MHC class II expression on the surface of plasma cells, which helps these cells to focus on antibody production rather than antigen presentation.

Which of the Following Is or Appears to Be Controlled