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PD-1 Is a Negative Costimulatory Signal Expressed by Tumor Cells

Question 13

Multiple Choice

PD-1 is a negative costimulatory signal expressed by tumor cells.What advantage would the expression of PD-1 have in a tumor cell avoiding the immune response?


A) Tumor cells can avoid being killed by activated TC cells.
B) Tumor cells can avoid apoptosis triggered by TH cells.
C) Tumor cells avoid phagocytosis by dendritic cells.
D) Tumor cells are stimulated to reproduce faster than tumor cells that do not express PD-1.
E) None.Tumor cells are recognized as self and, therefore, do not pose a health threat.

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