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Pathogenesis of Human Prion Disease Includes Which of the Following

Question 45

Multiple Choice

Pathogenesis of human prion disease includes which of the following?


A) during disease a conformational change in protein structure from 3% Beta-sheets to 43% Beta sheets occurs
B) prions are degraded by host cell proteases
C) neurons in the CNS become abnormally dense
D) PrPc prion protein induces conformational change in PrPsc proteins spreading the damage

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