Members of the Protozoal Genus Trypanosoma Include Species That Have

Members of the protozoal genus Trypanosoma include species that have programmed gene switching. This means that genes that produce primary surface antigens are shuffled to produce new combinations. How will this affect the pathogen? (Select all that apply)

A) previously produced host antibodies will not be able to recognize the antigens
B) host phagocytic cells will not be able to recognize and destroy the pathogen
C) some members of the species will always be able to survive the host's immune system
D) H and N mutations become so numerous that the resulting proteins cannot be recognized by previously produced antibodies