The Nurse Is Preparing to Administer Two Inhalations of Ipratropium

The nurse is preparing to administer two inhalations of ipratropium bromide (Atrovent) .When providing this medication,the nurse will instruct the patient to(Select all that apply.)

A) hold the canister horizontally.
B) keep the eyes closed.
C) exhale through the mouthpiece.
D) wait 15 seconds before the second inhalation.
E) shake the canister thoroughly prior to use.