Mr Tate, who weighs 80 kg, is to have 200 mg/kg of drug M, to be given intravenously over 45 minutes. Stock on hand is a 10% solution in 250 ml. The volume/hour required for this 45-minute order is

Question

Quizplus · Accepted Answer

First, calculate the total mg of drug M needed for Mr. Tate: 80 kg * 200 mg/kg = 16,000 mg. A 10% solution means 10 g of drug per 100 ml, so 250 ml contains 25 g or 25,000 mg. To get the volume of solution needed to deliver 16,000 mg: (16,000 mg / 25,000 mg) * 250 ml = 160 ml. Since this volume needs to be administered over 45 minutes, to find the rate in ml/hour: (160 ml / 45 min) * 60 min/hour = 213.3 ml/hour.

Mr Tate, Who Weighs 80 Kg, Is to Have 200