Newer "second-generation" antihistamines such as cetirizine (Zyrtec)and desloratidine (Clarinex)may be preferred to traditional antihistamines because these newer drugs

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Second-generation antihistamines, such as cetirizine and desloratadine, are preferred over first-generation antihistamines primarily because they are less likely to cross the blood-brain barrier, which reduces the risk of central nervous system side effects like drowsiness. They are selective for the H1 receptor subtype, which makes them effective in treating allergic reactions without the unwanted effects on other histamine receptor subtypes. Therefore, options A, B, and C are incorrect descriptions of the advantages of second-generation antihistamines.

Newer "Second-Generation" Antihistamines Such as Cetirizine (Zyrtec)and Desloratidine (Clarinex)may Be