Which of the following serum enzymes is the most reliable marker of extrahepatic biliary obstruction?
A) Alanine aminotransferase
B) Aspartate aminotransferase
C) Creatine kinase
D) Amylase
E) Alkaline phosphatase

Question

Quizplus · Accepted Answer

Alkaline phosphatase is the most reliable marker of extrahepatic biliary obstruction because it is produced by cells in the biliary tract and is released into the bloodstream when there is obstruction. Alanine aminotransferase (A) and aspartate aminotransferase (B) are liver enzymes and may be elevated in a variety of liver disorders, but are not specific to biliary obstruction. Creatine kinase (C) and amylase (D) are enzymes related to muscle and pancreas respectively, and are not related to biliary obstruction.

Which of the Following Serum Enzymes Is the Most Reliable