A 50-Year-Old Woman Calls the Clinic Because She Has Noticed

A 50-year-old woman calls the clinic because she has noticed some changes in her body and breasts and wonders if they could be due to the hormone replacement therapy (HRT) she started 3 months ago.The nurse should tell her:

A) "Hormone replacement therapy is at such a low dose that side effects are very unusual."
B) "Hormone replacement therapy has several side effects, including fluid retention, breast tenderness, and vaginal bleeding."
C) "It would be very unusual to have vaginal bleeding with hormone replacement therapy, and I suggest you come in to the clinic immediately to have this evaluated."
D) "It sounds as if your dose of estrogen is too high; I think you may need to decrease the amount you are taking and then call back in a week."