An indication placebo pain relief is real is that it:

Question

Quizplus · Accepted Answer

The fact that placebo pain relief can be blocked with naloxone suggests that it is mediated by the body's endogenous opioid system. Naloxone is an opioid antagonist that blocks the effects of opioids, including endorphins. Therefore, if placebo pain relief is blocked by naloxone, it suggests that endogenous opioids are involved in the mechanism of action. Amplication of placebo pain relief with naloxone has not been demonstrated. The claim that placebo pain relief only happens to highly hypnotizable individuals is not supported by the scientific literature, as placebo effects have been observed in a wide range of individuals.

An Indication Placebo Pain Relief Is Real Is That It