Placebo pain relief appears to work through endorphin circuitry,namely ___.

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Placebo pain relief appears to work through the release of endorphins in the periacqueductal gray (PAG), a region of the brain that modulates pain signals. Endorphins are the body's natural painkillers, and the release of these neurotransmitters can decrease the perception of pain. Research has shown that placebo-induced analgesia is blocked by administering drugs that inhibit endorphin release in the PAG, suggesting that endorphin circuitry plays a key role in placebo pain relief.

Placebo Pain Relief Appears to Work Through Endorphin Circuitry,namely ___