One potential way to treat pain might focus on blocking ___ that are deactivated in individuals with congenital pain insensitivity.

Question

Quizplus · Accepted Answer

Sodium ion channels are responsible for the generation and propagation of action potentials in neurons that transmit pain signals. Individuals with congenital pain insensitivity have mutations in genes that affect these channels, leading to a lack of pain sensation. By targeting these channels, it may be possible to block pain signals in individuals who experience chronic pain. This approach is already used in some pain medications, such as local anesthetics. Blocking mu or delta receptors or substance P receptors may also provide pain relief, but there is no direct evidence that these receptors are affected in individuals with congenital pain insensitivity.

One Potential Way to Treat Pain Might Focus on Blocking