Long-term depression is a decrease in the potency of a synapse when ___.
A)presynaptic neurons are active and postsynaptic neurons fire at the same time
B)presynaptic neurons are active and postsynaptic neurons are not depolarized at the same time
C)presynaptic neurons are depolarized and postsynaptic neurons fire at the same time
D)presynaptic neurons and postsynaptic neurons are depolarized at the same time

Question

Quizplus · Accepted Answer

Long-term depression occurs when presynaptic neurons are active and postsynaptic neurons are not depolarized at the same time. This leads to a decrease in the potency of the synapse, meaning that the strength of the connection between the two neurons is decreased. This can be a result of a lack of activation of the postsynaptic neuron, leading to a decrease in the strength of the synapse over time.

Long-Term Depression Is a Decrease in the Potency of a Synapse