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PTEN Is a Tumor Suppressor Gene in the Akt Signaling

Question 91

Multiple Choice

PTEN is a tumor suppressor gene in the Akt signaling pathway. Which statement about PTEN/Akt is false?


A) PIP2 can be oncogenically mutated to induce cell survival.
B) PTEN antagonizes (has the opposite effect) of PI 3-kinase.
C) Akt can be oncogenically mutated to induce cell survival.
D) It is a lipid phosphatase that dephosphorylates PIP3 to PIP2.

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