The binding of Hedgehog to the receptor Patched releases a transcription factor from actin microfilaments that enters the nucleus and turns on genes.

Question

Quizplus · Accepted Answer

The binding of Hedgehog to the receptor Patched actually relieves the inhibition on another protein called Smoothened, which then initiates a signaling cascade that ultimately leads to the activation of transcription factors (like Gli proteins in vertebrates) that enter the nucleus and turn on genes. The process does not involve the release of a transcription factor from actin microfilaments.

The Binding of Hedgehog to the Receptor Patched Releases a Transcription