The major difference between bipolar disorder and major depressive disorder is that in bipolar disorder there is:

Name: The major difference between bipolar disorder and major depressive disorder is that in bipolar disorder there is:
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The major difference between bipolar disorder and major depressive disorder is the presence of a mania component in bipolar disorder. Major depressive disorder does not involve episodes of mania, whereas bipolar disorder includes both depressive and manic episodes.

The Major Difference Between Bipolar Disorder and Major Depressive Disorder