Neurofibrillary tangles are
A) clumps of dead neurons in the brains of Alzheimer's patients.
B) senile plaques in the brains of Alzheimer's patients.
C) abnormal whorls of neurofilaments.
D) patches of dead and dying axons.

Question

Quizplus · Accepted Answer

Neurofibrillary tangles are abnormal whorls of neurofilaments that occur in the brains of individuals with Alzheimer's disease. They are made up of a protein called tau, which normally helps to stabilize the structure of neurons. In Alzheimer's disease, however, tau becomes hyperphosphorylated and forms tangled structures within the neurons, disrupting normal cellular processes and leading to cell death.

Neurofibrillary Tangles Are