A young male has non-Hodgkin's lymphoma. The LMO starts prednisone whilst awaiting a haematology admission. He presents unwell with WCC previously 30, now 2, urate 2.3, K 8.0, phosphate 10, Cr .25. The most likely diagnosis?

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Tumor lysis syndrome is the most likely diagnosis given the presentation of acute kidney injury (elevated creatinine), hyperkalemia (K 8.0), hyperphosphatemia (phosphate 10), and hyperuricemia (urate 2.3) following the initiation of chemotherapy in a patient with a high tumor burden, such as non-Hodgkin's lymphoma. These symptoms are characteristic of tumor lysis syndrome, a potentially life-threatening condition caused by the rapid release of intracellular contents from lysed cancer cells into the bloodstream.

A Young Male Has Non-Hodgkin's Lymphoma