What event served as a capstone summarizing many losses experienced by the Lakota and other indigenous peoples?

Name: What event served as a capstone summarizing many losses experienced by the Lakota and other indigenous peoples?
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The Wounded Knee Massacre, which occurred on December 29, 1890, is often cited as a tragic capstone to the many losses experienced by the Lakota and other indigenous peoples, symbolizing the culmination of a long series of conflicts, broken treaties, and forced relocations.

What Event Served as a Capstone Summarizing Many Losses Experienced