An 18-week-old male develops pneumonia and otitis media due to Streptococcus pneumoniae. Eventually, the child becomes septic with the same organism. While the peripheral blood demonstrates the presence of lymphocytes, there are no detectable antibody levels of IgG, IgM, IgA, IgD, and IgE. This child may be an example of

Question

Quizplus · Accepted Answer

Bruton's agammaglobulinemia is characterized by the absence of B cells, leading to very low levels of all immunoglobulin classes (IgG, IgM, IgA, IgD, and IgE), which explains the lack of detectable antibodies in the patient.

An 18-Week-Old Male Develops Pneumonia and Otitis Media Due to Streptococcus