The microbiology department received a notice that its last susceptibility media shipment is being recalled due to increased levels of thymine. If any of the medium was used for susceptibility testing, what antibiotic(s) would be affected?

Question

Quizplus · Accepted Answer

Trimethoprim-sulfamethoxazole's effectiveness can be influenced by the level of thymine in the medium because this antibiotic combination targets the folate synthesis pathway. Increased levels of thymine can bypass the blockade caused by trimethoprim, leading to false resistance readings.

The Microbiology Department Received a Notice That Its Last Susceptibility