A Man Tells the Nurse That His Father Died of Prostate

A man tells the nurse that his father died of prostate cancer and he is concerned about his own risk of developing the disease, having heard that prostate cancer has a genetic link. What aspect of the pathophysiology of prostate cancer would underlie the nurses response?

A) A number of studies have identified an association of BRCA-2 mutation with an increased risk of prostate cancer.
B) HNPCC is a mutation of two genes that causes prostate cancer in men and it is autosomal dominant.
C) Studies have shown that the presence of the TP53 gene strongly influences the incidence of prostate cancer.
D) Recent research has demonstrated that prostate cancer is the result of lifestyle factors and that genetics are unrelated.