Given the following laboratory information, what is the most probable metabolic bone disease?
Calcium - decreased
Phosphorus - decreased
PTH - increased
Alkaline phosphatase - increased
Calcidiol - decreased or normal
Calcitriol - decreased or normal

Question

Quizplus · Accepted Answer

Osteomalacia is seen when bones fail to mineralize.This failure is usually due to vitamin D deficiency or other related problems.The decrease in calcidiol and calcitriol correlates with this vitamin D deficiency.The decrease in calcitriol will result in decreased absorption of calcium and phosphorus.The resulting hypocalcemia and hypophosphatemia will stimulate an increased production of PTH.Although alkaline phosphatase lacks specificity for bone disease, the elevated activity does correlate with osteomalacia.Osteoporosis can be ruled out because normal calcium and phosphorus levels and a normal PTH are anticipated in this disease.Osteitis fibrosa can be ruled out because normal to elevated calcium and phosphorus levels, normal calcidiol, and normal to elevated calcitriol levels are anticipated in this disease.

Given the Following Laboratory Information, What Is the Most Probable