Which of the following is true of structural chromosomal abnormalities?
1)They are usually the result of aneuploidy.
2)They include translocations, deletions, inversions, and duplications.
3)They may be balanced or unbalanced.
4)They usually result from DNA damage due to exposure to radiation and toxic chemicals.

Question

Quizplus · Accepted Answer

Numerical chromosomal aberrations are usually the result of aneuploidy, or abnormal numbers of particular chromosomes.Structural chromosomal abnormalities are the result of defects in the normal chromosome structure or genomic sequence.These include translocations, deletions, inversions, and duplications, in addition to rarer abnormalities.Structural chromosomal abnormalities may be balanced (a rearrangement occurs, but no genetic material is presumably lost) or unbalanced (genetic material is lost).They usually result from DNA damage due to exposure to radiation and toxic chemicals or to abnormal function of the DNA recombination machinery.

Which of the Following Is True of Structural Chromosomal Abnormalities