A 45-Year-Old Corporate Executive Presents with the Primary Complaint of "Always

A 45-year-old corporate executive presents with the primary complaint of "always being tired." She comments that she has been tired for 4 months even though she is sleeping more. She complains of being unable to finish chores at home and "dragging at work." She indicates that she is often constipated and is intolerant of cold. She is continuously turning the thermostats in the house and office to higher temperatures, to the dismay of family and coworkers. She also complains that her skin is very dry; use of lotions and creams have not helped the dryness. A biopsy of her thyroid gland shows dense lymphocytic infiltration with germinal centers throughout the parenchyma and a battery of further tests is carried out, which also suggest thyroiditis. Which of the following results of blood tests would be most likely in this patient?

A) Elevated TSH levels
B) Elevated $\mathrm{T}_{3}$ and $\mathrm{T}_{4}$ levels
C) Autoantibodies to the thyroid hormone receptor
D) Elevated calcitonin levels
E) Elevated glucocorticoid levels