Allergies to Topical Anesthetic Drugs That Manifest in Mucosal Signs

Allergies to topical anesthetic drugs that manifest in mucosal signs and symptoms hours or days after application:

A) Are usually an indication of allergy to amide type anesthetics and all amide drugs should be avoided in the future
B) Are considered delayed hypersensitivity reactions however the drug type should be avoided in the future
C) Have a high potential to progress to anaphylaxis
D) Usually occur due to secondary infections from needle penetrations