Which of the Following Best Explains the Membrane Expansion Theory

Which of the following best explains the membrane expansion theory?

A) Membrane ion channels narrow due to diffusion of local anesthetic molecules into lipophilic regions of the membranes
B) Membrane ion channels narrow due to diffusion of local anesthetic molecules into hydrophilic regions of the membranes
C) Diffusion of local anesthetic molecules bind in the nerve channels causing a narrowing of lipophilic ion channels
D) Dissociation of local anesthesia molecules narrows membrane channels blocking influx of sodium and calcium ions