Which of the following familial cancers results from a defect in the tumor suppressor gene, p53?

Question

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Li Fraumeni syndrome is associated with mutations in the p53 tumor suppressor gene, leading to a predisposition to various types of cancer.  Li-Fraumeni syndrome (LFS) is a rare autosomal dominant disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults. LFS is linked to germline mutations in the tumor suppressor gene, p53.

Which of the Following Familial Cancers Results from a Defect