Which of the following is a systemic adverse reaction to corticosteroid treatment of ulcerative colitis?

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Corticosteroids prescribed to treat ulcerative colitis and Crohn's may be administered by mouth or rectally in the form of an enema or suppository.Adverse effects resulting from rectal administration may be local (burning and itching)or systemic (nausea,constipation or diarrhea,appetite changes,headache).

Which of the Following Is a Systemic Adverse Reaction to Corticosteroid