What is a consequence of plasma membrane damage to the mitochondria?
A)Enzymatic digestion halts DNA synthesis.
B)Influx of calcium ions halts ATP production.
C)Reduction in ATP production caused by edema from an influx in sodium
D)Shift of potassium out of the mitochondria, which destroys the infrastructure

Question

Quizplus · Accepted Answer

The most serious consequence of plasma membrane damage is, as in hypoxic injury, to the mitochondria. An influx of calcium ions from the extracellular compartment activates multiple enzyme systems resulting in cytoskeleton disruption, membrane damage, activation of inflammation, and eventually DNA degradation. Calcium ion accumulation in the mitochondria causes the mitochondria to swell, an occurrence that is associated with irreversible cellular injury. The injured mitochondria can no longer generate ATP, but they do continue to accumulate calcium ions.

What Is a Consequence of Plasma Membrane Damage to the Mitochondria